Which of the following mitosis phases involve the centrosomes completely migrating to the poles and the chromosomes aligning in the middle of the cell?

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The correct phase that involves the centrosomes completely migrating to the poles and the chromosomes aligning in the middle of the cell is during metaphase.

During metaphase, the chromosomes, which have been duplicated and condensed, are aligned along the metaphase plate (the equatorial plane of the cell). At this stage, the spindle fibers emanating from the centrosomes connect to the chromosomes at their centromeres, ensuring proper alignment and preparation for segregation.

In prophase, the chromosomes begin to condense and become visible, and the mitotic spindle starts to form, but the alignment of chromosomes in the middle of the cell does not occur yet; they are not fully aligned at this stage. Anaphase follows metaphase and is characterized by the separation of sister chromatids moving away from the center of the cell toward the poles. Telophase marks the end of mitosis, where the chromosomes decondense and the nuclear envelope reforms, but this is after the chromosomes have been separated.

Thus, the phase that specifically involves the centrosomes migrating to the poles and the chromosomes aligning in the middle is indeed metaphase.

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